Structure of PDB 2pam Chain B

Receptor sequence

>2pamB (length=134) Species: 143495 (Aneurinibacillus thermoaerophilus)

ENKVINFKKIIDSRGSLVAIEENKNIPFSIKRVYYIFDTKGEEPRGFNAN
KKLEQVLVCLNGSCRVILDDGNIIQEITLDSPAVGLYVGPAVWHEMHDFS
SDCVMMVLASDYYDETDYIRQYDNFKKYIAKINL

3D structure

• PDB: 2pam The X-ray Structure of dTDP-4-Keto-6-deoxy-D-glucose-3,4-ketoisomerase.
• Chain: B
• Resolution: 2.5 Å

Enzymatic activity

• Enzyme Commision number: 5.3.2.3: TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6- deoxy-alpha-D-galactopyranose-forming).

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	TYD	B	R15 A20	R14 A19
BS02	TYD	B	R33 Y35 Y114	R32 Y34 Y113

Gene Ontology

Molecular Function

• GO:0016853 isomerase activity

External links

• PDB: RCSB:2pam, PDBe:2pam, PDBj:2pam
• PDBsum: 2pam
• PubMed: 17459872
• UniProt: Q6T1W8|FDTA_ANETH TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (Gene Name=fdtA)