Structure of PDB 2p9k Chain B

Receptor sequence
>2p9kB (length=275) Species: 9913 (Bos taurus) [Search protein sequence]
VVCDNGTGFVKCGYAGSNFPEHIFPSYPMENWDDMKLLTEPPMNPTKNRA
IQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDI
TRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTV
LVESYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAA
DIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSK
FKIRIEDPPRRKHMVFLGGAVLADI
3D structure
PDB2p9k Insights into the Influence of Nucleotides on Actin Family Proteins from Seven Structures of Arp2/3 Complex.
ChainB
Resolution2.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP B G14 T15 G16 F17 K19 G160 D161 G186 R214 K217 E218 G306 M309 Y310 G6 T7 G8 F9 K11 G71 D72 G97 R125 K128 E129 G217 M220 Y221
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0051015 actin filament binding
Biological Process
GO:0010592 positive regulation of lamellipodium assembly
GO:0034314 Arp2/3 complex-mediated actin nucleation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:1905168 positive regulation of double-strand break repair via homologous recombination
GO:2001032 regulation of double-strand break repair via nonhomologous end joining
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005885 Arp2/3 protein complex
GO:0005938 cell cortex
GO:0035861 site of double-strand break
GO:0042995 cell projection

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2p9k, PDBe:2p9k, PDBj:2p9k
PDBsum2p9k
PubMed17499050
UniProtA7MB62|ARP2_BOVIN Actin-related protein 2 (Gene Name=ACTR2)

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