Structure of PDB 2p8e Chain B

Receptor sequence
>2p8eB (length=281) Species: 9606 (Homo sapiens) [Search protein sequence]
FLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDW
SFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRSVENVKNGIRTGFLKID
EYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCF
STQDHKPCNPREKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKG
PTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEYVKSRLEV
SDDLENVCNWVVDTCLHKGSRDNMSIVLVCF
3D structure
PDB2p8e Structural genomics of protein phosphatases.
ChainB
Resolution1.816 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B D60 D243 D286 D57 D229 D272
Gene Ontology
Molecular Function
GO:0004722 protein serine/threonine phosphatase activity
GO:0043169 cation binding
Biological Process
GO:0006470 protein dephosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2p8e, PDBe:2p8e, PDBj:2p8e
PDBsum2p8e
PubMed18058037
UniProtO75688|PPM1B_HUMAN Protein phosphatase 1B (Gene Name=PPM1B)

[Back to BioLiP]