Structure of PDB 2p7c Chain B

Receptor sequence
>2p7cB (length=82) Species: 1402 (Bacillus licheniformis) [Search protein sequence]
MKKIPQISDAELEVMKVIWKHSSINTNEVIKELSKTSTWSPKTIQTMLLR
LIKKGALNHHKEGRVFVYTPNIDESDYIEVKS
3D structure
PDB2p7c Conformational and thermodynamic changes of the repressor/DNA operator complex upon monomerization shed new light on regulation mechanisms of bacterial resistance against beta-lactam antibiotics.
ChainB
ResolutionN/A
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B N25 T26 N27 Q45 L49 R50 H59 K61 V65 F66 N25 T26 N27 Q45 L49 R50 H59 K61 V65 F66 PDBbind-CN: Kd=190uM
BS02 dna B P5 Q6 A10 E11 K42 T43 T46 M47 R50 L51 K54 K61 R64 P5 Q6 A10 E11 K42 T43 T46 M47 R50 L51 K54 K61 R64 PDBbind-CN: Kd=190uM
Gene Ontology
Biological Process
GO:0045892 negative regulation of DNA-templated transcription

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2p7c, PDBe:2p7c, PDBj:2p7c
PDBsum2p7c
PubMed17576674
UniProtP06555|BLAI_BACLI Penicillinase repressor (Gene Name=blaI)

[Back to BioLiP]