Structure of PDB 2p5o Chain B

Receptor sequence
>2p5oB (length=771) Species: 12353 (Escherichia phage RB69) [Search protein sequence]
MKEFYLTVEQIGDSIFERYIDSNGRERTREVEYKPSLFAHCPESQATKYF
DIYGKPCTRKLFANMRDASQWIKRMEDIGLEALGMDDFKLAYLSDTYNYE
IKYDHTKIRVANFDIEVTSPDGFPEPSQAKHPIDAITHYDSIDDRFYVFD
LLNSPYGNVEEWSIEIAAKLQEQGGDEVPSEIIDKIIYMPFDNEKELLME
YLNFWQQKTPVILTGWNVESFAIPYVYNRIKNIFGESTAKRLSPHRKTRV
KVIENMEIITLFGISVLDYIDLYKKFSFTNQPSYSLDYISEFELNVGKLK
YDGPISKLRESNHQRYISYNIIAVYRVLQIDAKRQFINLSLDMGYYAKIQ
IQSVFSPIKTWDAIIFNSLKEQNKVIPQGRSHPVQPYPGAFVKEPIPNRY
KYVMSFDLTSLYPSIIRQVNISPETIAGTFKVAPLHDYINAVAERPSDVY
SCSPNGMMYYKDRDGVVPTEITKVFNQRKEHKGYMLAAQRNMLFRAQRTE
VAGMTAQINRKLLINSLYGALGNVWFRYYDLRNATAITTFGQMALQWIER
KVNEYLNEVCGTEGEAFVLYGDTDSIYVSADKIIDKVGESKFRDTNHWVD
FLDKFARERMEPAIDRGFREMCEYMNNKQHLMFMDREAIAGPPLGSKGIG
GFWTGKKRYALNVWDMEGTRYAEPKLKIMGLETQKSSTPKAVQKALKECI
RRMLQEGEESLQEYFKEFEKEFRQLNYISIDVLHWMDYTVLLEKTFIKPL
EGFTSAAKLDYEKKASLFDMF
3D structure
PDB2p5o Crystallographic snapshots of a replicative DNA polymerase encountering an abasic site.
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.11.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B E116 V117 G122 F123 N217 F221 S287 Y288 S289 L290 S735 E116 V117 G122 F123 N217 F221 S283 Y284 S285 L286 S686
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004527 exonuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0039686 bidirectional double-stranded viral DNA replication
GO:0039693 viral DNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:2p5o, PDBe:2p5o, PDBj:2p5o
PDBsum2p5o
PubMed15057283
UniProtQ38087|DPOL_BPR69 DNA-directed DNA polymerase (Gene Name=43)

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