Structure of PDB 2p1p Chain B

Receptor sequence
>2p1pB (length=571) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
SFPEEVLEHVFSFIQLDKDRNSVSLVCKSWYEIERWCRRKVFIGNCYAVS
PATVIRRFPKVRSVELKGKPHFADFNLVPDGWGGYVYPWIEAMSSSYTWL
EEIRLKRMVVTDDCLELIAKSFKNFKVLVLSSCEGFSTDGLAAIAATCRN
LKELDLRESDVDDVSGHWLSHFPDTYTSLVSLNISCLASEVSFSALERLV
TRCPNLKSLKLNRAVPLEKLATLLQRAPQLEELGTGGYTAEVRPDVYSGL
SVALSGCKELRCLSGFWDAVPAYLPAVYSVCSRLTTLNLSYATVQSYDLV
KLLCQCPKLQRLWVLDYIEDAGLEVLASTCKDLRELRVFPSEPFVMEPNV
ALTEQGLVSVSMGCPKLESVLYFCRQMTNAALITIARNRPNMTRFRLCII
EPKAPDYLTLEPLDIGFGAIVEHCKDLRRLSLSGLLTDKVFEYIGTYAKK
MEMLSVAFAGDSDLGMHHVLSGCDSLRKLEIRDCPFGDKALLANASKLET
MRSLWMSSCSVSFGACKLLGQKMPKLNVEVIDERGAPDSRPESCPVERVF
IYRTVAGPRFDMPGFVWNMDQ
3D structure
PDB2p1p Mechanism of auxin perception by the TIR1 ubiquitin ligase
ChainB
Resolution2.21 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IHP B K74 H78 K113 R114 R344 R401 R436 M460 R484 K485 R509 K67 H71 K106 R107 R337 R394 R429 M453 R477 K478 R502
BS02 IAC B F79 R403 L404 S438 L439 S462 V463 A464 R489 F72 R396 L397 S431 L432 S455 V456 A457 R482
Gene Ontology
Molecular Function
GO:0000822 inositol hexakisphosphate binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0010011 auxin binding
GO:0038198 auxin receptor activity
Biological Process
GO:0006952 defense response
GO:0009733 response to auxin
GO:0009734 auxin-activated signaling pathway
GO:0009873 ethylene-activated signaling pathway
GO:0010152 pollen maturation
GO:0010311 lateral root formation
GO:0016036 cellular response to phosphate starvation
GO:0016567 protein ubiquitination
GO:0048443 stamen development
Cellular Component
GO:0005634 nucleus
GO:0019005 SCF ubiquitin ligase complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2p1p, PDBe:2p1p, PDBj:2p1p
PDBsum2p1p
PubMed17410169
UniProtQ570C0|TIR1_ARATH Protein TRANSPORT INHIBITOR RESPONSE 1 (Gene Name=TIR1)

[Back to BioLiP]