Structure of PDB 2p1o Chain B

Receptor sequence
>2p1oB (length=571) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
SFPEEVLEHVFSFIQLDKDRNSVSLVCKSWYEIERWCRRKVFIGNCYAVS
PATVIRRFPKVRSVELKGKPHFADFNLVPDGWGGYVYPWIEAMSSSYTWL
EEIRLKRMVVTDDCLELIAKSFKNFKVLVLSSCEGFSTDGLAAIAATCRN
LKELDLRESDVDDVSGHWLSHFPDTYTSLVSLNISCLASEVSFSALERLV
TRCPNLKSLKLNRAVPLEKLATLLQRAPQLEELGTGGYTAEVRPDVYSGL
SVALSGCKELRCLSGFWDAVPAYLPAVYSVCSRLTTLNLSYATVQSYDLV
KLLCQCPKLQRLWVLDYIEDAGLEVLASTCKDLRELRVFPSEPFVMEPNV
ALTEQGLVSVSMGCPKLESVLYFCRQMTNAALITIARNRPNMTRFRLCII
EPKAPDYLTLEPLDIGFGAIVEHCKDLRRLSLSGLLTDKVFEYIGTYAKK
MEMLSVAFAGDSDLGMHHVLSGCDSLRKLEIRDCPFGDKALLANASKLET
MRSLWMSSCSVSFGACKLLGQKMPKLNVEVIDERGAPDSRPESCPVERVF
IYRTVAGPRFDMPGFVWNMDQ
3D structure
PDB2p1o Mechanism of auxin perception by the TIR1 ubiquitin ligase
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B D81 F82 S139 P350 F351 F380 C405 I407 R489 D74 F75 S132 P343 F344 F373 C398 I400 R482
BS02 IHP B K74 K113 R114 R344 R401 R436 R484 K485 R509 K67 K106 R107 R337 R394 R429 R477 K478 R502
BS03 NLA B F79 R403 L404 C405 S438 L439 F72 R396 L397 C398 S431 L432
Gene Ontology
Molecular Function
GO:0000822 inositol hexakisphosphate binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0010011 auxin binding
GO:0038198 auxin receptor activity
Biological Process
GO:0006952 defense response
GO:0009733 response to auxin
GO:0009734 auxin-activated signaling pathway
GO:0009873 ethylene-activated signaling pathway
GO:0010152 pollen maturation
GO:0010311 lateral root formation
GO:0016036 cellular response to phosphate starvation
GO:0016567 protein ubiquitination
GO:0048443 stamen development
Cellular Component
GO:0005634 nucleus
GO:0019005 SCF ubiquitin ligase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2p1o, PDBe:2p1o, PDBj:2p1o
PDBsum2p1o
PubMed17410169
UniProtQ570C0|TIR1_ARATH Protein TRANSPORT INHIBITOR RESPONSE 1 (Gene Name=TIR1)

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