Structure of PDB 2p15 Chain B

Receptor sequence
>2p15B (length=242) Species: 9606 (Homo sapiens) [Search protein sequence]
LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTFTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL
LILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRLH
3D structure
PDB2p15 Structural plasticity in the oestrogen receptor ligand-binding domain.
ChainB
Resolution1.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 V376 E380 D538 E542 M543 I53 K57 L67 V71 E75 D230 E234 M235
BS02 EZT B M343 L346 E353 L387 F404 M421 I424 F425 H524 M38 L41 E48 L82 F99 M116 I119 F120 H216
External links
PDB RCSB:2p15, PDBe:2p15, PDBj:2p15
PDBsum2p15
PubMed17468738
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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