Structure of PDB 2ovr Chain B

Receptor sequence
>2ovrB (length=442) Species: 9606 (Homo sapiens) [Search protein sequence]
TQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWR
ILAEDNLLWREKCKEEGIDEPLHIKRVIKPGFIHSPWKSAYIRQHRIDTN
WRRGELKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCL
RTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTV
RCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRV
VSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIR
VWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCL
QTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLE
SGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDM
3D structure
PDB2ovr Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B W2425 R2465 R2479 R2505 Y2519 W161 R201 R215 R241 Y255
External links
PDB RCSB:2ovr, PDBe:2ovr, PDBj:2ovr
PDBsum2ovr
PubMed17434132
UniProtQ969H0|FBXW7_HUMAN F-box/WD repeat-containing protein 7 (Gene Name=FBXW7)

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