Structure of PDB 2ovq Chain B

Receptor sequence
>2ovqB (length=444) Species: 9606 (Homo sapiens) [Search protein sequence]
TQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWR
ILAEDNLLWREKCKEEGIDEPLHIKRRKVIKPGFIHSPWKSAYIRQHRID
TNWRRGELKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGK
CLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTS
TVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGR
RVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTS
IRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQ
CLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVT
LESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDM
3D structure
PDB2ovq Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases
ChainB
Resolution2.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B W2425 S2462 T2463 R2465 R2479 R2505 Y2519 A2599 T2628 D2642 R2689 W163 S200 T201 R203 R217 R243 Y257 A337 T366 D380 R427
External links
PDB RCSB:2ovq, PDBe:2ovq, PDBj:2ovq
PDBsum2ovq
PubMed17434132
UniProtQ969H0|FBXW7_HUMAN F-box/WD repeat-containing protein 7 (Gene Name=FBXW7)

[Back to BioLiP]