Structure of PDB 2ork Chain B

Receptor sequence
>2orkB (length=151) Species: 9606 (Homo sapiens) [Search protein sequence]
ASLRQQVEALQGQVQHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPF
TEAQLLCTQAGGQLASPRSAAENAALQQLVVAKNEAAFLSMTDSKTEGKF
TYPTGESLVYSNWAPGEPNDDGGSEDCVEIFTNGKWNDRACGEKRLVVCE
F
3D structure
PDB2ork Critical Role of Arg/Lys343 in the Species-Dependent Recognition of Phosphatidylinositol by Pulmonary Surfactant Protein D.
ChainB
Resolution1.89 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B E321 N323 E329 N341 D342 E117 N119 E125 N137 D138
BS02 CA B D297 E301 D324 E329 D330 D93 E97 D120 E125 D126
BS03 CA B E301 D330 E97 D126
BS04 IPD B E321 N323 E329 N341 R343 E117 N119 E125 N137 R139 MOAD: ic50=1.4mM
PDBbind-CN: -logKd/Ki=2.85,IC50=1.4mM
External links
PDB RCSB:2ork, PDBe:2ork, PDBj:2ork
PDBsum2ork
PubMed17417879
UniProtP35247|SFTPD_HUMAN Pulmonary surfactant-associated protein D (Gene Name=SFTPD)

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