Structure of PDB 2o88 Chain B

Receptor sequence
>2o88B (length=56) Species: 9606 (Homo sapiens) [Search protein sequence]
NLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPS
AYITPV
3D structure
PDB2o88 Crystallization by capillary counter-diffusion and structure determination of the N114A mutant of the SH3 domain of Abl tyrosine kinase complexed with a high-affinity peptide ligand.
ChainB
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y70 D77 W99 W110 Y115 Y7 D14 W36 W47 Y52
External links
PDB RCSB:2o88, PDBe:2o88, PDBj:2o88
PDBsum2o88
PubMed17452790
UniProtP00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 (Gene Name=ABL1)

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