Structure of PDB 2o74 Chain B

Receptor sequence
>2o74B (length=164) Species: 7955 (Danio rerio) [Search protein sequence]
DINVVNALAYEDFVKLFGNVVEKCPLISAAIWSYRPFKDLADIEARISEF
IHSLPDSGKEGILRCHPDLAGRDLQSGTLTPESQEEQSQAGMTTLDSAEI
VHMYRLNSEYKERFGFPFVICARLNNKADIVRQLSERLKNRRTAELECAI
EEVKKICSLRLHSI
3D structure
PDB2o74 The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation.
ChainB
Resolution1.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 4.1.1.97: 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GUN B P68 L70 S84 E87 V120 I121 A123 I157 P67 L69 S83 E86 V119 I120 A122 I156
Gene Ontology
Molecular Function
GO:0016831 carboxy-lyase activity
GO:0051997 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity
Biological Process
GO:0000255 allantoin metabolic process
GO:0006144 purine nucleobase metabolic process
GO:0019628 urate catabolic process
Cellular Component
GO:0005777 peroxisome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2o74, PDBe:2o74, PDBj:2o74
PDBsum2o74
PubMed17428786
UniProtA1L259|URAD_DANRE 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (Gene Name=urad)

[Back to BioLiP]