Structure of PDB 2o61 Chain B

Receptor sequence
>2o61B (length=314) Species: 9606 (Homo sapiens) [Search protein sequence]
MDGPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICN
YVGPAKVIVQLVTNGKNIHLHAHSLVGKHCEDGICTVTAGPKDMVVGFAN
LGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQAEGGGDRQL
GDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDA
IYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEE
ENGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSD
LETSEPKPFLYYPE
3D structure
PDB2o61 An Atomic Model of the Interferon-beta Enhanceosome.
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B R54 R56 S63 H64 G65 R18 R20 S27 H28 G29
BS02 dna B Y57 C59 K144 K275 R305 Y21 C23 K108 K239 R269
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2o61, PDBe:2o61, PDBj:2o61
PDBsum2o61
PubMed17574024
UniProtP19838|NFKB1_HUMAN Nuclear factor NF-kappa-B p105 subunit (Gene Name=NFKB1)

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