Structure of PDB 2o52 Chain B

Receptor sequence
>2o52B (length=158) Species: 9606 (Homo sapiens) [Search protein sequence]
SDFLFKFLVIGSAGTGKSCLLHQFIEVEFGSRVVNVGGKTVKLQIWDTAG
QERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVV
ILCGNKKDLDPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCA
RTILNKID
3D structure
PDB2o52 Crystal structure of human RAB4B in complex with GDP
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GDP B G18 T19 G20 K21 S22 C23 N121 K122 D124 L125 S151 A152 L153 G14 T15 G16 K17 S18 C19 N105 K106 D108 L109 S135 A136 L137
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0032482 Rab protein signal transduction

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Molecular Function

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Biological Process
External links
PDB RCSB:2o52, PDBe:2o52, PDBj:2o52
PDBsum2o52
PubMed
UniProtP61018|RAB4B_HUMAN Ras-related protein Rab-4B (Gene Name=RAB4B)

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