Structure of PDB 2nuf Chain B

Receptor sequence
>2nufB (length=219) Species: 63363 (Aquifex aeolicus) [Search protein sequence]
KMLEQLEKKLGYTFKDKSLLEKALTHVSYSKKEHYETLEFLGDALVNFFI
VDLLVQYSPNKREGFLSPLKAYLISEEFFNLLAQKLELHKFIRIKRGKIN
ETIIGDVFEALWAAVYIDSGRDANFTRELFYKLFKEDILSAIKEGRVKKD
YKTILQEITQKRWKERPEYRLISVEGPHHKKKFIVEAKIKEYRTLGEGKS
KKEAEQRAAEELIKLLEES
3D structure
PDB2nuf A stepwise model for double-stranded RNA processing by ribonuclease III.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.26.3: ribonuclease III.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B E64 G65 S68 K150 D151 K153 T154 Q157 E158 Q161 K165 R167 E63 G64 S67 K149 D150 K152 T153 Q156 E157 Q160 K164 R166
BS02 rna B H27 V28 R97 N101 H179 H180 F184 K200 K202 H26 V27 R96 N100 H178 H179 F183 K199 K201
BS03 MG B D44 E110 D43 E109
BS04 MG B E40 D107 E110 E39 D106 E109
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0004519 endonuclease activity
GO:0004525 ribonuclease III activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0008033 tRNA processing
GO:0010468 regulation of gene expression
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2nuf, PDBe:2nuf, PDBj:2nuf
PDBsum2nuf
PubMed18047582
UniProtO67082|RNC_AQUAE Ribonuclease 3 (Gene Name=rnc)

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