Structure of PDB 2nny Chain B

Receptor sequence
>2nnyB (length=129) Species: 9606 (Homo sapiens) [Search protein sequence]
VRDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSSQSFISWT
GDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAG
KRYVYRFVSDLQSLLGYTPEELHAMLDVK
3D structure
PDB2nny Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization.
ChainB
Resolution2.58 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B Q336 L337 K379 K381 M384 K388 R391 Y395 Y396 Q29 L30 K72 K74 M77 K81 R84 Y88 Y89
BS02 dna B Y386 R391 R394 Y397 K404 R409 Y410 Y79 R84 R87 Y90 K97 R102 Y103
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:2nny, PDBe:2nny, PDBj:2nny
PDBsum2nny
PubMed18566588
UniProtP14921|ETS1_HUMAN Protein C-ets-1 (Gene Name=ETS1)

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