Structure of PDB 2mpi Chain B

Receptor sequence
>2mpiB (length=30) Species: 9606 (Homo sapiens) [Search protein sequence]
FVNQHLCGSDLVEALYLVCGERGGFYTKPT
3D structure
PDB2mpi Protective hinge in insulin opens to enable its receptor engagement.
ChainB
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B F22 V23 N24 Q25 H26 L27 C28 L36 V39 C40 F1 V2 N3 Q4 H5 L6 C7 L15 V18 C19
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:2mpi, PDBe:2mpi, PDBj:2mpi
PDBsum2mpi
PubMed25092300
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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