Structure of PDB 2mli Chain B

Receptor sequence
>2mliB (length=30) Species: 9606 (Homo sapiens) [Search protein sequence]
FVNQHLCGSDLVEALYLVCGERGFFYTKPT
3D structure
PDB2mli Protective hinge in insulin opens to enable its receptor engagement.
ChainB
ResolutionN/A
3D
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B F22 N24 Q25 H26 L27 C28 L32 A35 L36 V39 C40 R43 G44 F45 X46 Y47 F1 N3 Q4 H5 L6 C7 L11 A14 L15 V18 C19 R22 G23 F24 X25 Y26
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:2mli, PDBe:2mli, PDBj:2mli
PDBsum2mli
PubMed25092300
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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