Structure of PDB 2lgb Chain B
Receptor sequence
>2lgbB (length=31) Species:
9606
(Homo sapiens) [
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FVNQHLCGSHLVEALYLVCGERGFFYTPKTR
3D structure
PDB
2lgb
Recombinant A22(G)-B31 (R)-human insulin. A22 addition introduces conformational mobility in B chain C-terminus.
Chain
B
Resolution
N/A
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
B
F101 N103 Q104 H105 L106 C107 L111 L115 V118 C119 G123 R131
F1 N3 Q4 H5 L6 C7 L11 L15 V18 C19 G23 R31
Gene Ontology
Molecular Function
GO:0005179
hormone activity
Cellular Component
GO:0005576
extracellular region
View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB
RCSB:2lgb
,
PDBe:2lgb
,
PDBj:2lgb
PDBsum
2lgb
PubMed
22350952
UniProt
P01308
|INS_HUMAN Insulin (Gene Name=INS)
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