Structure of PDB 2lgb Chain B

Receptor sequence
>2lgbB (length=31) Species: 9606 (Homo sapiens) [Search protein sequence]
FVNQHLCGSHLVEALYLVCGERGFFYTPKTR
3D structure
PDB2lgb Recombinant A22(G)-B31 (R)-human insulin. A22 addition introduces conformational mobility in B chain C-terminus.
ChainB
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B F101 N103 Q104 H105 L106 C107 L111 L115 V118 C119 G123 R131 F1 N3 Q4 H5 L6 C7 L11 L15 V18 C19 G23 R31
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:2lgb, PDBe:2lgb, PDBj:2lgb
PDBsum2lgb
PubMed22350952
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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