Structure of PDB 2l2k Chain B

Receptor sequence
>2l2kB (length=71) Species: 10090 (Mus musculus) [Search protein sequence]
PSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRN
KKLAKARAAQSALATVFNLHL
3D structure
PDB2l2k The Solution Structure of the ADAR2 dsRBM-RNA Complex Reveals a Sequence-Specific Readout of the Minor Groove.
ChainB
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.4.37: double-stranded RNA adenine deaminase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna B P43 K46 N47 M50 E54 S70 H71 F75 R91 N92 K93 K94 K97 P1 K4 N5 M8 E12 S28 H29 F33 R49 N50 K51 K52 K55 PDBbind-CN: Kd=370nM
External links
PDB RCSB:2l2k, PDBe:2l2k, PDBj:2l2k
PDBsum2l2k
PubMed20946981
UniProtQ91ZS8|RED1_MOUSE Double-stranded RNA-specific editase 1 (Gene Name=Adarb1)

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