Structure of PDB 2kxn Chain B

Receptor sequence
>2kxnB (length=95) Species: 9606 (Homo sapiens) [Search protein sequence]
RHVGNRANPDPNCCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQS
RRSRGFAFVYFENVDDAKEAKERANGMELDGRRIRVDFSITKRPH
3D structure
PDB2kxn Molecular basis of purine-rich RNA recognition by the human SR-like protein Tra2-beta1
ChainB
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna B R111 F123 G124 S148 I149 V150 R159 F161 F163 Y165 R187 R188 R190 S194 I195 T196 K197 R198 P199 H200 R6 F18 G19 S43 I44 V45 R54 F56 F58 Y60 R82 R83 R85 S89 I90 T91 K92 R93 P94 H95 PDBbind-CN: Kd=2.25uM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:2kxn, PDBe:2kxn, PDBj:2kxn
PDBsum2kxn
PubMed21399644
UniProtP62995|TRA2B_HUMAN Transformer-2 protein homolog beta (Gene Name=TRA2B)

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