Structure of PDB 2jlf Chain B

Receptor sequence
>2jlfB (length=661) Species: 10879 (Cystovirus phi6) [Search protein sequence]
RAPAFPLSDIKAQMLFANNIKAQQASKRSFKEGAIETYEGLLSVDPRFLS
FKNELSRYLTDHFPANVDEYGRVYGNGVRTNFFGMRHMNGFPMIPATWPL
ASNLKKRADADLADGPVSERDNLLFRAAVRLMFSDLEPVPLKIRKGSSTC
IPYFSNDMGTKIEIAERALEKAEEAGNLMLQGKFDDAYQLHQMGGAYYVV
YRAQSTDAITLDPKTGKFVSKDRMVADFEYAVTGGEQGSLFAASKDASRL
KEQYGIDVPDGFFCERRRTAMGGPFALNAPIMAVAQPVRNKIYSKYAYTF
HHTTRLNKEEKVKEWSLCVATDVSDHDTFWPGWLRDLICDELLNMGYAPW
WVKLFETSLKLPVYVGAPAPEQGHTLLGDPSNPDLEVGLSSGQGATDLMG
TLLMSITYLVMQLDHTAPHLNSRIKDMPSACRFLDSYWQGHEEIRQISKS
DDAMLGWTKGRALVGGHRLFEMLKEGKVNPSPYMKISYQHGGAFLGDILL
YDSRREPGSAIFVGNINSMLNNQFSPEYGVQSGVRDRSKRKRPFPGLAWA
SMKDTYGACPIYSDVLEAIERCWWNAFGESYRAYREDMLKRDTLELSRYV
ASMARQAGLAELTPIDLEVLADPNKLQYKWTEADVSANIHEVLMHGVSVE
KTERFLRSVMP
3D structure
PDB2jlf Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase.
ChainB
Resolution3.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN B D454 Q491 A495 D452 Q489 A493
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
GO:0050265 RNA uridylyltransferase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0019079 viral genome replication
GO:0039694 viral RNA genome replication
Cellular Component
GO:0044423 virion component

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2jlf, PDBe:2jlf, PDBj:2jlf
PDBsum2jlf
PubMed18940872
UniProtP11124|RDRP_BPPH6 RNA-directed RNA polymerase (Gene Name=P2)

[Back to BioLiP]