Structure of PDB 2jky Chain B

Receptor sequence
>2jkyB (length=202) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
DKQYISYNNVHQLCQVSAERIKNFKPDLIIAIGGGGFIPARILRTFLKEP
GVPTIRIFAIILSLYEDLNVGVKVSRTQWIDYEQCKLDLVGKNVLIVDEV
DDTRTTLHYALSELEKDAAEQAKAKGIDTEKSPEMKTNFGIFVLHDKQKP
KKADLPAEMLNDKNRYFAAKTVPDKWYAYPWESTDIVFHTRMAIEQGNDI
FI
3D structure
PDB2jky Functional Significance of Four Successive Glycine Residues in the Pyrophosphate Binding Loop of Fungal 6-Oxopurine Phosphoribosyltransferases.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.8: hypoxanthine phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5GP B D110 E111 V112 D114 T115 R116 T117 T118 K159 W188 Y189 Y191 E194 D98 E99 V100 D102 T103 R104 T105 T106 K147 W176 Y177 Y179 E182
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004422 hypoxanthine phosphoribosyltransferase activity
GO:0016757 glycosyltransferase activity
GO:0046872 metal ion binding
GO:0052657 guanine phosphoribosyltransferase activity
Biological Process
GO:0006166 purine ribonucleoside salvage
GO:0009058 biosynthetic process
GO:0032263 GMP salvage
GO:0032264 IMP salvage
GO:0032265 XMP salvage
GO:0046100 hypoxanthine metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2jky, PDBe:2jky, PDBj:2jky
PDBsum2jky
PubMed22610485
UniProtQ04178|HPRT_YEAST Hypoxanthine-guanine phosphoribosyltransferase (Gene Name=HPT1)

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