Structure of PDB 2j90 Chain B

Receptor sequence
>2j90B (length=264) Species: 9606 (Homo sapiens) [Search protein sequence]
HYEMGEELGSGQFAIVRKCRQKEYAAKFIKKRRLSSSRRGVSREEIEREV
NILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKSLTEDEA
TQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAH
KIEAGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASP
FLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLVKDPKRRMTI
AQSLEHSWIKAIRR
3D structure
PDB2j90 Activation Segment Dimerization: A Mechanism for Kinase Autophosphorylation of Non-Consensus Sites.
ChainB
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) D139 K141 E143 N144 D161 T180
Catalytic site (residue number reindexed from 1) D123 K125 E127 N128 D145 T164
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IZA B L19 V27 A40 L93 E94 L95 V96 M146 I160 D161 L8 V16 A25 L78 E79 L80 V81 M130 I144 D145
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2j90, PDBe:2j90, PDBj:2j90
PDBsum2j90
PubMed18239682
UniProtO43293|DAPK3_HUMAN Death-associated protein kinase 3 (Gene Name=DAPK3)

[Back to BioLiP]