Structure of PDB 2iya Chain B

Receptor sequence
>2iyaB (length=384) Species: 1890 (Streptomyces antibioticus) [Search protein sequence]
VTPRHISFFNIPGHGHVNPSLGIVQELVARGHRVSYAITDEFAAQVKAAG
ATPVVYDSILPKESNPEESWPEDQESAMGLFLDEAVRVLPQLEDAYADDR
PDLIVYDIASWPAPVLGRKWDIPFVQLSPTFVAYEGFEEDVPAVQDPTAD
GLVRFFTRLSAFLEEHGVDTPATEFLIAPNRCIVALPRTFQIKGDTVGDN
YTFVGPTYGDRSWEGRPVLLIALGSAFTDHLDFYRTCLSAVDGLDWHVVL
SVGRFVDPADLGEVPPNVEVHQWVPQLDILTKASAFITHAGMGSTMEALS
NAVPMVAVPQIAEQTMNAERIVELGLGRHIPRDQVTAEKLREAVLAVASD
PGVAERLAAVRQEIREAGGARAAADILEGILAEA
3D structure
PDB2iya The Crystal Structure of Two Macrolide Glycosyltransferases Provides a Blueprint for Host Cell Antibiotic Immunity.
ChainB
Resolution1.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.4.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UDP B G24 R242 S264 W312 V313 Q315 H328 G330 G332 S333 E336 G15 R211 S225 W273 V274 Q276 H289 G291 G293 S294 E297
BS02 ZIO B H25 W79 Q83 A86 M87 F90 F140 F146 L207 A351 E352 H16 W70 Q74 A77 M78 F81 F131 F137 L176 A312 E313
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008194 UDP-glycosyltransferase activity
GO:0016740 transferase activity
GO:0016758 hexosyltransferase activity
Biological Process
GO:0017000 antibiotic biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2iya, PDBe:2iya, PDBj:2iya
PDBsum2iya
PubMed17376874
UniProtQ3HTL7

[Back to BioLiP]