Structure of PDB 2iw6 Chain B

Receptor sequence
>2iw6B (length=257) Species: 9606 (Homo sapiens) [Search protein sequence]
PDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEY
KLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEV
AEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPA
NCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPES
LIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLLN
PPETLNL
3D structure
PDB2iw6 Dissecting the Determinants of Cyclin-Dependent Kinase 2 and Cyclin-Dependent Kinase 4 Inhibitor Selectivity.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B M200 Q203 I206 M25 Q28 I31
Gene Ontology
Molecular Function
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0044772 mitotic cell cycle phase transition

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Molecular Function
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Biological Process
External links
PDB RCSB:2iw6, PDBe:2iw6, PDBj:2iw6
PDBsum2iw6
PubMed16942020
UniProtP20248|CCNA2_HUMAN Cyclin-A2 (Gene Name=CCNA2)

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