Structure of PDB 2iv9 Chain B

Receptor sequence
>2iv9B (length=233) Species: 9606 (Homo sapiens) [Search protein sequence]
GGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFA
IQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQ
VAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQI
KECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELR
IQPGNPNYTLSLKCRAPEVSQYIYQVYDSILKN
3D structure
PDB2iv9 Role of the Ap2 Beta-Appendage Hub in Recruiting Partners for Clathrin-Coated Vesicle Assembly
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B W714 K719 P799 N802 S817 C818 L819 W10 K15 P95 N98 S113 C114 L115
Gene Ontology
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030117 membrane coat
GO:0030131 clathrin adaptor complex

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Biological Process

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Cellular Component
External links
PDB RCSB:2iv9, PDBe:2iv9, PDBj:2iv9
PDBsum2iv9
PubMed16903783
UniProtP63010|AP2B1_HUMAN AP-2 complex subunit beta (Gene Name=AP2B1)

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