Structure of PDB 2iss Chain B

Receptor sequence
>2issB (length=285) Species: 2336 (Thermotoga maritima) [Search protein sequence]
PRGSHMEIKKGTWIIKKGFAEMFKGGVIMDVTSAEQAKIAEEAGAVAVMA
LERVPADIRKEGGVARMASIAKIREIMEAVSIPVMAKVRIGHIAEAKILE
ELGVDFIDESEVLTPADDRFHINKHEFKVPFVCGARDLGEALRRIAEGAA
MIRTKGEAGTGNVVEAVKHMRRVMEQIKQVTKMEDEELVAYGKEIGAPVE
LLREVKRLGRLPVVNFAAGGVATPADAALMMMLGADGVFVGSGIFKSKDP
RKMAKAMVLAVTYWDNPRILLKISEDIGEPMRGLD
3D structure
PDB2iss Structural Insights into the Mechanism of the PLP Synthase Holoenzyme from Thermotoga maritima
ChainB
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.3.3.6: pyridoxal 5'-phosphate synthase (glutamine hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5RP B D25 P50 K82 D103 R148 A153 G154 G214 G215 G236 S237 D30 P55 K87 D108 R153 A158 G159 G219 G220 G241 S242
Gene Ontology
Molecular Function
GO:0016829 lyase activity
GO:0016843 amine-lyase activity
GO:0036381 pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity
Biological Process
GO:0006520 amino acid metabolic process
GO:0008615 pyridoxine biosynthetic process
GO:0042819 vitamin B6 biosynthetic process
GO:0042823 pyridoxal phosphate biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2iss, PDBe:2iss, PDBj:2iss
PDBsum2iss
PubMed17144654
UniProtQ9WYU4|PDXS_THEMA Pyridoxal 5'-phosphate synthase subunit PdxS (Gene Name=pdxS)

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