Structure of PDB 2ipk Chain B

Receptor sequence
>2ipkB (length=190) Species: 9606 (Homo sapiens) [Search protein sequence]
GDTRPRFLWQLKFECHFFNGTERVRLLERCIYNQEESVRFDSDVGEYRAV
TELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVEPKVT
VYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQN
GDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA
3D structure
PDB2ipk Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B L11 F13 D57 Y60 W61 L67 R71 Y78 H81 N82 V85 G86 F89 L11 F13 D57 Y60 W61 L67 R71 Y78 H81 N82 V85 G86 F89
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2ipk, PDBe:2ipk, PDBj:2ipk
PDBsum2ipk
PubMed17351628
UniProtP01911|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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