Structure of PDB 2ifw Chain B

Receptor sequence
>2ifwB (length=206) Species: 5539 (Scytalidium lignicola) [Search protein sequence]
TVESNWGGAILIGSDFDTVSATANVPSASGGSSAAGTAWVGIDGDTCQTA
ILQTGFDWYGDGTYDAWYEWYPEVSDDFSGITISEGDSIQMSVTATSDTS
GSATLENLTTGQKVSKSFSNESSGSLCRTNAEFIIEDFEECNSNGSDCEF
VPFASFSPAVEFTDCSVTSDGESVSLDDAQITQVIINNQDVTDCSVSGTT
VSCSYV
3D structure
PDB2ifw Crystal structure of scytalidoglutamic peptidase with its first potent inhibitor provides insights into substrate specificity and catalysis.
ChainB
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Q53 E136
Catalytic site (residue number reindexed from 1) Q53 E136
Enzyme Commision number 3.4.23.32: scytalidopepsin B.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B N5 W6 T37 G44 D45 Q48 I51 Q53 D65 W67 E69 Y71 V74 S75 D77 E136 F138 E139 E140 C141 N142 S143 N5 W6 T37 G44 D45 Q48 I51 Q53 D65 W67 E69 Y71 V74 S75 D77 E136 F138 E139 E140 C141 N142 S143
Gene Ontology
Molecular Function
GO:0070007 glutamic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2ifw, PDBe:2ifw, PDBj:2ifw
PDBsum2ifw
PubMed17069854
UniProtP15369|PRTB_SCYLI Scytalidopepsin B

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