Structure of PDB 2i74 Chain B

Receptor sequence
>2i74B (length=180) Species: 10090 (Mus musculus) [Search protein sequence]
ERKEILFIPSENEKISKQFHLRYDIVRDRYIRVSDNNTNISGWENGVWKM
ESIFRKVEKDWNMVYLARKEGSSFAYISWKFECGSAGLKVDTVSIRTSSQ
SFESGSVRWKLRSETAQVNLLGDKNLRSYNDFSGATEVTLEAELSRGDGD
VAWQHTQLFRQSLNDSGENGLEIIITFNDL
3D structure
PDB2i74 Structural and biochemical studies of the C-terminal domain of mouse peptide-N-glycanase identify it as a mannose-binding module.
ChainB
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.52: peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN B D531 W532 Q625 D60 W61 Q154
BS02 MAN B K527 W624 K56 W153
BS03 MAN B E529 W532 Q625 R631 E58 W61 Q154 R160
Gene Ontology
Biological Process
GO:0006516 glycoprotein catabolic process
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:2i74, PDBe:2i74, PDBj:2i74
PDBsum2i74
PubMed17088551
UniProtQ9JI78|NGLY1_MOUSE Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (Gene Name=Ngly1)

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