Structure of PDB 2hwg Chain B

Receptor sequence
>2hwgB (length=572) Species: 562 (Escherichia coli) [Search protein sequence]
ISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKAS
AQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTAD
AAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSA
IQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPA
IVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASEKA
ELAKLKDLPAITLDGHQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLF
MDRDALPTEEEQFAAYKAVAEACGSQAVIVRTMDIGGDKELPYMNFPKEE
NPFLGWRAIRIAMDRREILRDQLRAILRASAFGKLRIMFPMIISVEEVRA
LRKEIEIYKQELRDEGKAFDESIEIGVMVETPAAATIARHLAKEVDFFSI
GTNDLTQYTLAVDRGNDMISHLYQPMSPSVLNLIKQVIDASHAEGKWTGM
CGELAGDERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKVLAEQ
ALAQPTTDELMTLVNKFIEEKT
3D structure
PDB2hwg Structure of phosphorylated enzyme I, the phosphoenolpyruvate:sugar phosphotransferase system sugar translocation signal protein.
ChainB
Resolution2.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) P9 A104 H189 E431 S450 D455 C502 E522
Catalytic site (residue number reindexed from 1) P8 A103 H188 E430 S449 D454 C501 E521
Enzyme Commision number 2.7.3.9: phosphoenolpyruvate--protein phosphotransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B H189 E431 D455 H188 E430 D454
BS02 OXL B H189 R332 M429 E431 G452 N454 D455 H188 R331 M428 E430 G451 N453 D454
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0008965 phosphoenolpyruvate-protein phosphotransferase activity
GO:0016301 kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system
GO:0016310 phosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2hwg, PDBe:2hwg, PDBj:2hwg
PDBsum2hwg
PubMed17053069
UniProtP08839|PT1_ECOLI Phosphoenolpyruvate-protein phosphotransferase (Gene Name=ptsI)

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