Structure of PDB 2hvw Chain B

Receptor sequence
>2hvwB (length=146) Species: 1309 (Streptococcus mutans) [Search protein sequence]
RLSWQDYFMANAELISKRSTCNRAYVGAVLVKNNRIIATGYNGGVADTDN
CDDVGHEMEDGHCIRTVHAEMNALIQCAKEGISANNTEIYVTHFPCINCT
KALLQAGVKKITYNTAYRIHPFAIELMTQKEVEYVQHDVPRVKLGE
3D structure
PDB2hvw Crystal structures of Streptococcus mutans 2'-deoxycytidylate deaminase and its complex with substrate analog and allosteric regulator dCTP x Mg2+.
ChainB
Resolution1.67 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.5.4.12: dCMP deaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C24 C54 H59 C66 C21 C51 H56 C63
BS02 ZN B H71 C99 C102 H68 C96 C99
BS03 DCP B R21 G43 Y44 G46 G47 A49 N75 R18 G40 Y41 G43 G44 A46 N72
BS04 DDN B C24 R26 A27 V29 N45 H65 C66 T69 H71 E73 C99 Y120 R121 C21 R23 A24 V26 N42 H62 C63 T66 H68 E70 C96 Y117 R118
BS05 DCP B R4 W7 N37 R38 R1 W4 N34 R35
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:2hvw, PDBe:2hvw, PDBj:2hvw
PDBsum2hvw
PubMed18255096
UniProtQ8DSE5

[Back to BioLiP]