Structure of PDB 2hv8 Chain B

Receptor sequence
>2hv8B (length=169) Species: 9606 (Homo sapiens) [Search protein sequence]
EYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVD
GKTIKAQIWDTAGLERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWL
KELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSAL
DSTNVEAAFQTILTEIYRI
3D structure
PDB2hv8 Structural Basis for Rab11-mediated Recruitment of FIP3 to Recycling Endosomes.
ChainB
Resolution1.86 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 2ME B R129 R132 R123 R126
BS02 MG B S25 T43 S19 T37
BS03 GTP B S20 G21 G23 K24 S25 N26 F36 N37 L38 S40 S42 T43 A68 N124 K125 D127 L128 S154 A155 L156 S14 G15 G17 K18 S19 N20 F30 N31 L32 S34 S36 T37 A62 N118 K119 D121 L122 S148 A149 L150
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:2hv8, PDBe:2hv8, PDBj:2hv8
PDBsum2hv8
PubMed17007872
UniProtP62491|RB11A_HUMAN Ras-related protein Rab-11A (Gene Name=RAB11A)

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