Structure of PDB 2huw Chain B

Receptor sequence
>2huwB (length=98) Species: 9606 (Homo sapiens) [Search protein sequence]
KPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDV
QHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQ
3D structure
PDB2huw Ligand Preorganization May Be Accompanied by Entropic Penalties in Protein-Ligand Interactions.
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YVN B R67 R86 S88 E89 S90 S96 Q106 H107 F108 K109 L120 W121 R12 R31 S33 E34 S35 S41 Q51 H52 F53 K54 L65 W66 MOAD: Ka=1000000M^-1
External links
PDB RCSB:2huw, PDBe:2huw, PDBj:2huw
PDBsum2huw
PubMed17001728
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

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