Structure of PDB 2huf Chain B

Receptor sequence
>2hufB (length=385) Species: 7159 (Aedes aegypti) [Search protein sequence]
MEYKVTPPAVLREPLVTPNKLLMGPGPSNAPQRVLDAMSRPILGHLHPET
LKIMDDIKEGVRYLFQTNNIATFCLSASGHGGMEATLCNLLEDGDVILIG
HTGHWGDRSADMATRYGADVRVVKSKVGQSLSLDEIRDALLIHKPSVLFL
TQGDSSTGVLQGLEGVGALCHQHNCLLIVDTVASLGGAPMFMDRWEIDAM
YTGSQKVLGAPPGITPVSFSHRAVERYKRRNTKVKVYYWDMSLVGDYWGC
FGRPRIYHHTISSTLLYGLREAIAMACEEGLPALIARHEDCAKRLYRGLQ
DAGFELYADPKDRLSTVTTIKVPQGVDWLKAAQYAMKTYLVEISGGLGPT
AGQVFRIGLMGQNATTERVDRVLQVFQEAVAAVKP
3D structure
PDB2huf Crystal Structures of Aedes aegypti Alanine Glyoxylate Aminotransferase.
ChainB
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.6.1.44: alanine--glyoxylate transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1BO B H45 Y257 H45 Y257
BS02 1BO B S155 L347 R356 S155 L347 R356
Gene Ontology
Molecular Function
GO:0004760 L-serine-pyruvate transaminase activity
GO:0008453 alanine-glyoxylate transaminase activity
GO:0008483 transaminase activity
GO:0016740 transferase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0009436 glyoxylate catabolic process
GO:0019265 glycine biosynthetic process, by transamination of glyoxylate
Cellular Component
GO:0005777 peroxisome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2huf, PDBe:2huf, PDBj:2huf
PDBsum2huf
PubMed16990263
UniProtQ3LSM4|AGT_AEDAE Alanine--glyoxylate aminotransferase (Gene Name=AGT)

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