Structure of PDB 2ht9 Chain B

Receptor sequence
>2ht9B (length=111) Species: 9606 (Homo sapiens) [Search protein sequence]
TAPVNQIQETISDNCVVIFSKTSCSYCTMAKKLFHDMNVNYKVVELDLLE
YGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKLLPLVHQC
YLKKSKRKEFQ
3D structure
PDB2ht9 Reversible sequestration of active site cysteines in a 2Fe-2S-bridged dimer provides a mechanism for glutaredoxin 2 regulation in human mitochondria
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GSH B S36 S38 S23 S25
BS02 FES B C37 S38 Y39 C24 S25 Y26
BS03 GSH B K34 C37 Y39 Q69 T80 V81 G93 A94 T95 K21 C24 Y26 Q56 T67 V68 G80 A81 T82
External links
PDB RCSB:2ht9, PDBe:2ht9, PDBj:2ht9
PDBsum2ht9
PubMed17121859
UniProtQ9NS18|GLRX2_HUMAN Glutaredoxin-2, mitochondrial (Gene Name=GLRX2)

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