Structure of PDB 2hhh Chain B

Receptor sequence
>2hhhB (length=234) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
VKELLEAGVHFGHERKRWNPKFARYIYAERNGIHIIDLQKTMEELERTFR
FIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNFK
TISQRVHRLEELEALFASPEIEERPKKEQVRLKHELERLQKYLSGFRLLK
RLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGNDD
AIRSIQLILSRAVDLIIQARGGVVEPSPSYALVQ
3D structure
PDB2hhh The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.
ChainB
Resolution3.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B W24 P26 G99 G100 T103 N104 T107 R111 R144 I172 E176 K179 W18 P20 G93 G94 T97 N98 T101 R105 R138 I166 E170 K173
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2hhh, PDBe:2hhh, PDBj:2hhh
PDBsum2hhh
PubMed16998488
UniProtP80371|RS2_THET8 Small ribosomal subunit protein uS2 (Gene Name=rpsB)

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