Structure of PDB 2h8c Chain B

Receptor sequence
>2h8cB (length=116) Species: 562 (Escherichia coli) [Search protein sequence]
NTYSITLPWPPSNNRYYRHNRGRTHVSAEGQAYRDNVARIIKNAMLDIGL
AMPVKIRIECHMPDRRRRNLDNLQKAAFDALTKAGFWLDDAQVVDYRVVK
MPVTKGGRLELTITEM
3D structure
PDB2h8c RusA Holliday junction resolvase: DNA complex structure--insights into selectivity and specificity.
ChainB
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.10: crossover junction endodeoxyribonuclease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B N15 R67 R68 R69 N70 N73 N14 R66 R67 R68 N69 N72
BS02 dna B D65 R66 R67 D64 R65 R66
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0000400 four-way junction DNA binding
GO:0004519 endonuclease activity
GO:0008821 crossover junction DNA endonuclease activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006310 DNA recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:2h8c, PDBe:2h8c, PDBj:2h8c
PDBsum2h8c
PubMed17028102
UniProtP0AG74|RUSA_ECOLI Crossover junction endodeoxyribonuclease RusA (Gene Name=rusA)

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