Structure of PDB 2gxa Chain B

Receptor sequence
>2gxaB (length=270) [Search protein sequence]
TEKFDFGTMVQWAYDHKYAEESKIAYEYALAAGSDSNARAFLATNSQAKH
VKDCATMVRHYLRAETQALSMPAYIKARCKLATGEGSWKSILTFFNYQNI
ELITFINALKLWLKGIPKKNCLAFIGPPNTGKSMLCNSLIHFLGGSVLSF
ANHKSHFWLASLADTRAALVDDATHACWRYFDTYLRNALDGYPVSIDRKH
KAAVQIKAPPLLVTSNIDVQAEDRYLYLHSRVQTFRFEQPCTDESGEQPF
NITDADWKSFFVRLWGRLDL
3D structure
PDB2gxa Mechanism of DNA translocation in a replicative hexameric helicase.
ChainB
Resolution3.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B K506 H507 K199 H200
BS02 ADP B I423 P424 K425 I116 P117 K118
BS03 ADP B G438 K439 S440 N558 G131 K132 S133 N251
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0005524 ATP binding
Biological Process
GO:0006260 DNA replication

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Molecular Function
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Biological Process
External links
PDB RCSB:2gxa, PDBe:2gxa, PDBj:2gxa
PDBsum2gxa
PubMed16855583
UniProtP03116|VE1_BPV1 Replication protein E1 (Gene Name=E1)

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