Structure of PDB 2gt4 Chain B

Receptor sequence
>2gt4B (length=160) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MMFLRQEDFATVVRSTPLVSLDFIVENSRGEFLLGKRTNRPAQGYWFVPG
GRVQKDETLEAAFERLTMAELGLRLPITAGQFYGVWQHFYDDNFSGTDFT
THFVVLGFRFRVSEEELLLPDEQHDDYRWLTSDALLASDNVHANSRAYFL
AEKRTGVPGL
3D structure
PDB2gt4 X-ray, NMR, and mutational studies of the catalytic cycle of the GDP-mannose mannosyl hydrolase reaction.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BMA B R37 T38 N39 R37 T38 N39
BS02 MG B G50 E70 G50 E70
BS03 GDD B F3 L4 F9 S20 D22 R37 F47 G50 G51 R52 H88 Y90 F103 F3 L4 F9 S20 D22 R37 F47 G50 G51 R52 H88 Y90 F103
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0008727 GDP-mannose mannosyl hydrolase activity
GO:0016787 hydrolase activity
GO:0030145 manganese ion binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0047917 GDP-glucosidase activity
Biological Process
GO:0009103 lipopolysaccharide biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2gt4, PDBe:2gt4, PDBj:2gt4
PDBsum2gt4
PubMed16981689
UniProtP32056|GMM_ECOLI GDP-mannose mannosyl hydrolase (Gene Name=gmm)

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