Structure of PDB 2ght Chain B

Receptor sequence
>2ghtB (length=180) Species: 9606 (Homo sapiens) [Search protein sequence]
QYLLPEAKAQDSDKICVVINLDETLVHSSFKPVNNADFIIPVEIDGVVHQ
VYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARL
FRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWF
DNMSDTELHDLLPFFEQLSRVDDVYSVLRQ
3D structure
PDB2ght Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1.
ChainB
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B N96 L97 D98 F106 I120 D121 T152 A153 S154 L155 K157 Y158 R178 N187 Y188 S208 N20 L21 D22 F30 I44 D45 T76 A77 S78 L79 K81 Y82 R102 N111 Y112 S132
BS02 MG B N96 D98 N207 N20 D22 N131
Gene Ontology
Molecular Function
GO:0016791 phosphatase activity

View graph for
Molecular Function
External links
PDB RCSB:2ght, PDBe:2ght, PDBj:2ght
PDBsum2ght
PubMed17157258
UniProtQ9GZU7|CTDS1_HUMAN Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (Gene Name=CTDSP1)

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