Structure of PDB 2gfa Chain B

Receptor sequence
>2gfaB (length=110) Species: 9606 (Homo sapiens) [Search protein sequence]
LQSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPED
IVSGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRD
DVYTLDEELP
3D structure
PDB2gfa Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.66: [histone H3]-trimethyl-L-lysine(9) demethylase.
1.14.11.69: [histone H3]-trimethyl-L-lysine(36) demethylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B F932 D934 S936 F937 S938 N940 Y942 D945 W967 T968 Y973 F37 D39 S41 F42 S43 N45 Y47 D50 W66 T67 Y72
External links
PDB RCSB:2gfa, PDBe:2gfa, PDBj:2gfa
PDBsum2gfa
PubMed16601153
UniProtO75164|KDM4A_HUMAN Lysine-specific demethylase 4A (Gene Name=KDM4A)

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