Structure of PDB 2geq Chain B

Receptor sequence
>2geqB (length=189) Species: 10090 (Mus musculus) [Search protein sequence]
QKTYQGNYGFHLGFLQSVMCTYSPPLNKLFCQLAKTCPVQLWVSATPPAG
SRVRAMAIYKKSQHMTEVVRRCPHHERCSDGDGLAPPQHLIRVEGNLYPE
YLEDRQTFRHSVVVPYEPPEAGSEYTTIHYKYMCNSSCMGGMNRRPILTI
ITLEDSSGNLLGRDSFEVRVCACPGRDRRTEEENFRKKE
3D structure
PDB2geq Structure of the p53 Core Domain Dimer Bound to DNA.
ChainB
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B S238 R270 A273 R277 S137 R169 A172 R176
BS02 ZN B C173 H176 C239 C72 H75 C138
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2geq, PDBe:2geq, PDBj:2geq
PDBsum2geq
PubMed16717092
UniProtP02340|P53_MOUSE Cellular tumor antigen p53 (Gene Name=Tp53)

[Back to BioLiP]