Structure of PDB 2g77 Chain B

Receptor sequence
>2g77B (length=173) Species: 10090 (Mus musculus) [Search protein sequence]
RSRIFKIIVIGDSNVGKTCLTYRFCAGRFPDRTEATIGVDFRERAVDIDG
ERIKIQLWDTAGQERFRKSMVQHYYRNVHAVVFVYDMTNMASFHSLPAWI
EECKQHLLANDIPRILVGNKCDLRSAIQVPTDLAQKFADTHSMPLFETSA
KNPNDNDHVEAIFMTLAHKLKSH
3D structure
PDB2g77 TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism.
ChainB
Resolution2.26 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B T47 T65 T18 T36
BS02 GDP B N43 G45 K46 T47 C48 F58 T62 N148 K149 D151 S178 K180 N14 G16 K17 T18 C19 F29 T33 N119 K120 D122 S149 K151
BS03 AF3 B S42 K46 T65 A90 G91 S13 K17 T36 A61 G62
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0032482 Rab protein signal transduction

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Molecular Function
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Biological Process
External links
PDB RCSB:2g77, PDBe:2g77, PDBj:2g77
PDBsum2g77
PubMed16855591
UniProtO35963|RB33B_MOUSE Ras-related protein Rab-33B (Gene Name=Rab33b)

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