Structure of PDB 2fxf Chain B

Receptor sequence
>2fxfB (length=164) Species: 9606 (Homo sapiens) [Search protein sequence]
AKFVIRPATAADCSDILRLIKELAKYEYQVILTEKDLLEDGFGEHPFYHC
LVAEVPKEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFG
IGSEILKNLSQVAMRCRCSSMHFLVAEWNEPSINFYKRRGASDLEGWRLF
KIDKEYLLKMATEE
3D structure
PDB2fxf The Crystal Structure of Human spermidine/spermine N1-acetyltransferase
ChainB
Resolution2.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.1.57: diamine N-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B E92 D93 E88 D89
BS02 ACO B Y27 D93 F94 F95 V96 R101 G102 F103 G104 G106 S107 L128 S136 F139 Y140 R142 R143 Y26 D89 F90 F91 V92 R97 G98 F99 G100 G102 S103 L124 S132 F135 Y136 R138 R139
Gene Ontology
Molecular Function
GO:0004145 diamine N-acetyltransferase activity
GO:0005515 protein binding
GO:0008080 N-acetyltransferase activity
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0019809 spermidine binding
GO:0042802 identical protein binding
Biological Process
GO:0001525 angiogenesis
GO:0006596 polyamine biosynthetic process
GO:0009447 putrescine catabolic process
GO:0032918 spermidine acetylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2fxf, PDBe:2fxf, PDBj:2fxf
PDBsum2fxf
PubMed
UniProtP21673|SAT1_HUMAN Diamine acetyltransferase 1 (Gene Name=SAT1)

[Back to BioLiP]