Structure of PDB 2fu5 Chain B

Receptor sequence
>2fu5B (length=107) Species: 9606 (Homo sapiens) [Search protein sequence]
QGHMVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQLFLPSMRKDGDLLQ
EHWLVEDMFIFENVGFTKDVGNIKFLVCADCEIGPIGWHCLDDKNSFYVA
LERVSHE
3D structure
PDB2fu5 Nucleotide exchange via local protein unfolding-structure of Rab8 in complex with MSS4
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN B C23 C26 C94 C97 C17 C20 C78 C81
Gene Ontology
Molecular Function
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006892 post-Golgi vesicle-mediated transport
GO:0007264 small GTPase-mediated signal transduction
GO:0015031 protein transport
GO:0061025 membrane fusion
Cellular Component
GO:0005829 cytosol
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:2fu5, PDBe:2fu5, PDBj:2fu5
PDBsum2fu5
PubMed16541104
UniProtP47224|MSS4_HUMAN Guanine nucleotide exchange factor MSS4 (Gene Name=RABIF)

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