Structure of PDB 2fsh Chain B

Receptor sequence
>2fshB (length=722) Species: 562 (Escherichia coli) [Search protein sequence]
RNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLEN
LIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTA
TLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMP
APAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVD
SILIDEARTPLIISGPAEDSVLIEELLVKEGIMDEGESLYSPANIMLMHH
VTAAQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVV
VPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEK
SELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAGRGT
DIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLEAGGLHIIGTER
HESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLG
MKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYS
QRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLK
NDFDLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRH
FEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMF
AAMLESLKYEVISTLSKVQVRM
3D structure
PDB2fsh Structure of dimeric SecA, the Escherichia coli preprotein translocase motor.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.4.2.8: protein-secreting ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP B M81 R82 F84 Q87 T104 G105 G107 K108 T109 L110 R509 M69 R70 F72 Q75 T92 G93 G95 K96 T97 L98 R398
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0008564 protein-exporting ATPase activity
GO:0042802 identical protein binding
GO:0043021 ribonucleoprotein complex binding
GO:0043022 ribosome binding
GO:0046872 metal ion binding
GO:0070678 preprotein binding
Biological Process
GO:0006605 protein targeting
GO:0006612 protein targeting to membrane
GO:0006886 intracellular protein transport
GO:0009306 protein secretion
GO:0015031 protein transport
GO:0017038 protein import
GO:0043952 protein transport by the Sec complex
GO:0061077 chaperone-mediated protein folding
GO:0065002 intracellular protein transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009898 cytoplasmic side of plasma membrane
GO:0016020 membrane
GO:0031522 cell envelope Sec protein transport complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2fsh, PDBe:2fsh, PDBj:2fsh
PDBsum2fsh
PubMed17229438
UniProtP10408|SECA_ECOLI Protein translocase subunit SecA (Gene Name=secA)

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