Structure of PDB 2fr4 Chain B

Receptor sequence

>2fr4B (length=214) Species: 10090 (Mus musculus) [Search protein sequence]

QVKLLESGPELVKPGASVKMSCKASGYTFTSYVMHWVKQKPGQGLEWIGY
INPYNDGTKYNEKFKGKATLTSDKSSSTAYMELSSLTSEDSAVYYCVRGG
YRPYYAMDYWGQGTSVTVSSAKTTPPSVYPLAPGSMVTLGCLVKGYFPEP
VTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAH
PASSTKVDKKIVPR

3D structure

PDB

2fr4 Impact of DNA hairpin folding energetics on antibody-ssDNA association.

Chain

Resolution

1.95 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	B	Y97 R98 Y100 Y100A A100B	Y101 R102 Y104 Y105 A106	PDBbind-CN: Kd=4uM
BS02	dna	B	S31 Y53 Y97 R98	S31 Y54 Y101 R102	PDBbind-CN: Kd=4uM

External links

PDB	RCSB:2fr4, PDBe:2fr4, PDBj:2fr4
PDBsum	2fr4
PubMed	18028946

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